| Prenatal Tests & Screening | When is it done? | Why is it done? |
| Quantitative serum HcG | 5-8 weeks | Viable pregnancy, ectopic, SAB |
| CBC | 1st PN visit, prn | Anemia, infection |
| Antibody screen | 1st PN visit & at 28 weeks if + | Unusual antibodies, mom/baby incompatibilities |
| Blood type | 1st PN visit | Emergency transfusion |
| RH | 1st PN visit | If mom RH- & fetus RH+ could be incompatible. Rhogam at 28 wks, prn chance of mat/fetal bleed |
| U/A | 1st PN visit | Infection: esp asymptomatic |
| RPR | 1st PN visit | Syphilis |
| Rubella | 1st PN visit | Immunity. Offer vaccine postpartum |
| TB | 1st PN visit if at risk | Infection. Can be treated during pregnancy |
| Hepatitis B | 1st PN visit | Infection |
| TORCH, 5ths disease | 1st PN visit prn | Fetal well being |
| Integrated test: ultrasound, nuchal translucency (NT) | 10-13 weeks | Down Syndrome, Trisomy 13 and Trisomy 18 |
| Glucose: 1 hr gtt | 24-28 weeks and 1st PN visit if at risk | Gestational diabetes |
| AFP, triple marker, cystic fibrosis | 15-20 weeks | Neural tube defects, Down's, trisomy 18, cystic fibrosis |
| CVS | 10-12 weeks | Chromosomal abnormalities, still needs AFP |
| Amniocentesis | 15-20 weeks | Chromosomal abnormalities |
| HIV | 1st PN visit, 3rd trimester if HR, rapid test in labor | Maternal, fetal well-being |
| GC/Chlamydia | 1st PN visit | Infection |
| Ultrasound | 18-22 weeks (offer), 1st PN visit & prn | Dating, fetal, placental, uterine abnormalities |
| Pap Smear & possibly HPV | 1st PN visit | Cervical Cancer |
| Group B strep (vaginal) | 36 weeks | Prevent meningitis, pneumonia in newborn |
| Work & environmental hazards | 1st PN visit | Teratogens, safety, hours |
| Alcohol, tobacco | 1st PN visit | Fetal teratogens, effects on placental perfusion, maternal well-being |
| Illicit substance use | 1st PN visit | Fetal teratogens, effects on placenta |
| Domestic Violence | 1st PN visit, prn | Maternal & fetal safety |
| Dietary | 1st PN visit, 20 weeks | Maternal & fetal well-being |
| Dental | 1st PN visit | Maternal & fetal well-being |
| Living situation/homeless | 1st PN Visit, prn | Maternal & fetal well-being |