. Click on lecture topics to access
outlines Reading Date:
Topic:
1/27 1/29 Ch 1,2 2/3 Ch 2,5 2/5 Part 3 2/10 Part 4 2/12 Ch 2,6 2/17 Ch 5 2/19 Ch 15 2/24 NO CLASS- Independent assignment 2/26 Ch 15 3/2 Enveloped [+]
strand viruses; Toga-, Flavi-, & Corona-
viridae; "The Great
Paper Chase" begins- See
example Ch 15 3/4 [-] strand RNA
viruses; Rhabdo-,Paramyxo-, Orthomyxo-
viridae Ch 16 3/9 Ch 16 3/11 MIDTERM I [Through
ssRNA (+) strand viruses] 3/16 Double-stranded RNA
viruses; Reo-, Partiti- & Cysto-
viridae Ch 16 3/18 Viruses using reverse
transcriptase; Retroviridae;
*Paper Chase
question #4 proposals due Ch 20 3/23 Ch 21 3/25 Ch 17 3/30 Ch 17 4/1 Ch 17,18 4/5-9 SPRING
BREAK!!! 4/13 Ch 19 4/15 Myo- & Sipho-
viridae; "The Great
Paper Chase" ends Ch 19 4/20 pp 281-283 4/22 MIDTERM II [(-)
strand RNA viruses through DNA
viruses] 4/27 4/29 Expression control & strategies
continued 5/4 Ch 7,8 5/6 Ch 4 5/11 5/13 Emerging viruses &
future trends; Review Ch 22 5/18 FINAL 5-7
pm
Note on readings: The arrangement of material in
the Wagner book is such that you will need to be flexible
and fluid in finding and reading the appropriate parts. The
chapters listed above will direct you to some, but not all,
of the related information. Use of the index will be
indispensable. For some of the lecture topics, the
associated material is either not well isolated or is not
developed in the book. The Ackermann book is not so much
read as absorbed. The diagrams will help to anchor the
structures and functions of the viruses. Other references & resources: On reserve in
the library is a copy of Ackermann, et al., 1995, Atlas
of Virus Diagrams; Ackermann, et al., 1998, Virus
Life in Diagrams; and selected diagrams from Ackermann,
et al., 2001, Viral Pathogenesis in Diagrams,
arranged in page order, table of contents included. These
images, along with images from your texts will be used in
lecture. For methods, in addition
to Part 3 in Wagner, you will find on reserve Appendix 1
from Levy, et al., 1994, Virology. Also, the computer
exercises will introduce you to both on-line resources and
to on-line databases of current literature. You should find
the on-line information a valuable asset , allowing you to
readily extend beyond the limitations of the text. [back] Lecture organization & content: Lectures are
organized into 3 phases: 1) a comprehensive introduction of
molecular virology and principles relating to the study of
viruses, 2) an in-depth look at representative viruses,
starting with the smallest and simplest RNA viruses, then
progressing to successively more complex viruses to the
largest and most complex DNA viruses, followed by the
difficult-to-classify viroids and prions, and finally 3) a
comparative look at viral expression strategies, viral
pathogenic mechanisms, and host responses. Lecture material
is drawn from your texts, other reference texts, journal
literature, and on-line resources, including ICTV, NCBI, and
CDC. If you miss a lecture, be sure to get a copy of notes
from someone, since there is likely to be material not found
in your text. For your convenience, lecture note outlines
can be obtained by clicking on the linked lecture titles in
the schedule above. These should help you in your
background reading and should serve as a guide during
lecture. Date:
Room:
Topic:
1/27; D122 Group discussion: Current problems & issues
in virology; Discussion section mechanics 2/3; 2/5 D207 Viral structural modeling- computers &
development of handmade models [Lab scheduled
6:50-8:50] 2/10;2/12 D122 Viral structural model show- presentation of
models; Group discussion: Basic methodology-
choices 2/17;2/19 D207 Introduction to bioinformatics & databases;
Independent assignment: Bioinformatics searches
[Lab scheduled 6:50-8:50] 2/26 D122 Discussion: Bioinformatics; Review & study
strategies for midterm 3/2; 3/4 D207 Bioinformatics Project [Lab scheduled
6:50-8:50]; "The Great Paper Chase"
strategies 3/9 D122 Group discussion: Viruses as agents of
evolution; Review 3/16;3/18 D122 Bioinformatics- troubleshooting & using
applications 3/23; D122 Journal presentations 3/30; 4/1 D122 Journal presentations 4/5-9 SPRING
BREAK!!! 4/13; D122 Qualitative methods demonstration; Journal
presentations 4/20; D229 Quantitative assays: set
up [Be prepared to check your results 4/25
in D234] (Click link for lab
protocol) 4/27; D122 Quantitative assays: results; Journal
presentations 5/4; D122 Group discussion: Making an effective HIV
vaccine; Journal presentations 5/11; D122 Group discussion: Future issues in virology;
Journal presentations Date:
Topic:
3/23; 3/25 ssRNA viruses 3/30; 4/1 dsRNA viruses; retroviruses; hepadnaviruses 4/13; 4/15 DNA viruses 4/27; 4/29 Viroids; prions 5/4; 5/6 Infection control; vaccine development 5/11; 5/13 New & emerging viruses
Lecture
schedule
Spring, 2004 Lecture Schedule:
[top of page]
Texts: [back]
Wagner & Hewlett, 2004. Basic Virology 2e,
Blackwell Scientific.
[top of page]Spring, 2004 Discussion
Schedule
1/29
3/25
4/15
4/22
4/29
5/6
5/13
D207 Computer Lab; D229 = Molec/cell Lab
[top of page]Journal Presentations: Schedule of
topics
[top of page]
Updated 1/24/04 by thatcher@sonoma.edu